Zivolife’s immune-supporting properties are backed by its unique combination of bioactive compounds. The key nutrients found in Klebsormidium algae (Zivolife’s proprietary strain) that support immune function include:
1. Beta-Glucans (Immune System Activators)
Role in Immunity:
• Enhances macrophage and white blood cell activity, helping the body detect and fight infections.
• Stimulates cytokine production, crucial for immune signaling and response to pathogens.
• Modulates inflammation, preventing excessive immune reactions (e.g., in autoimmune diseases).
2. Polyphenols (Antioxidant & Anti-Inflammatory Agents)
Role in Immunity:
• Neutralizes free radicals, reducing oxidative stress that can weaken immune cells.
• Lowers chronic inflammation, which is linked to autoimmune conditions and immune dysfunction.
• Improves gut microbiome health, which indirectly strengthens immune function.
3. Carotenoids (Lutein, Zeaxanthin, Beta-Carotene)
Role in Immunity:
• Boosts T-cell activation, a key component of adaptive immunity.
• Enhances natural killer (NK) cell function, which helps fight infections and cancerous cells.
• Protects mucosal barriers (lungs, gut lining) against pathogens.
4. Vitamin A (Barrier & Cellular Immunity)
Role in Immunity:
• Maintains mucosal integrity (lungs, gut, and skin), preventing pathogen entry.
• Supports B-cell activation for antibody production.
• Plays a role in T-cell differentiation, helping the immune system recognize and respond to threats.
5. Vitamin B12 (Energy & Red Blood Cell Support)
Role in Immunity:
• Supports red blood cell production, which ensures oxygen delivery to immune cells.
• Helps with DNA synthesis, crucial for immune cell replication.
• Prevents immune suppression caused by B12 deficiency.
6. Vitamin E (Antioxidant for Immune Protection)
Role in Immunity:
• Protects immune cells from oxidative damage.
• Enhances B-cell activity, boosting antibody production.
• Improves immune responses in aging populations.
7. Iron (Oxygen Transport & Immune Cell Function)
Role in Immunity:
• Supports hemoglobin production, ensuring oxygen delivery to immune cells.
• Involved in T-cell function, which helps fight infections.
• Aids in the activation of immune responses to bacteria and viruses.
8. Essential Fatty Acids (Omega-3s & Glycerolipids)
Role in Immunity:
• Regulates inflammation to prevent excessive immune responses.
• Supports immune cell membrane integrity, improving communication between cells.
• Reduces chronic inflammation, linked to autoimmune conditions.
9. Pheophorbides (Chlorophyll-Derived Compounds)
Role in Immunity:
• Demonstrates anti-inflammatory activity by inhibiting nitric oxide production.
• Modulates nuclear factor kappaB (NF-κB) activation, reducing inflammation in immune-related diseases.
• May have antiviral and antimicrobial properties.
The ZIVO Patent
• Proprietary Strain: The ZIVO patent secures Klebsormidium algae as a unique, natural, and effective source of immune-supporting compounds.
• Scientifically Proven Effects: Nutrients like beta-glucans, polyphenols, and carotenoids have well-documented immune benefits.
• Broad Application Scope: The patent allows ZIVO to develop multiple immune-supporting products, including:
• Functional foods
• Nutritional supplements
• Medical foods
• Animal nutrition
ZIVO Bioscience has secured a U.S. patent (US11806375B2) in November 2023, covering the use of algal biomass from Klebsormidium species in food, feed, and nutritional supplements. This patent emphasizes the role of Klebsormidium in maintaining general health and promoting a healthy immune system in both humans and animals.
Additionally, in December 2019, ZIVO Bioscience filed patent applications for a novel polysaccharide molecular complex derived from their proprietary algal cultures. This complex has been optimized to inhibit inflammatory cytokine production, which is linked to immune-related diseases such as rheumatoid arthritis and inflammatory bowel disease.